• Diagnostic accuracy of anti-3-[18F]-FACBC PET/MRI in gliomas 

      Karlberg, Anna Maria; Pedersen, Lars Kjelsberg; Vindstad, Benedikte Emilie; Skjulsvik, Anne Jarstein; Johansen, Håkon; Solheim, Ole Skeidsvoll; Skogen, Karoline; Kvistad, Kjell Arne; Bogsrud, Trond; Myrmel, Kristin Smistad; Giskeødegård, Guro F.; Ingebrigtsen, Tor; Berntsen, Erik Magnus; Eikenes, Live (Peer reviewed; Journal article, 2023)
      Purpose - The primary aim was to evaluate whether anti-3-[18F]FACBC PET combined with conventional MRI correlated better with histomolecular diagnosis (reference standard) than MRI alone in glioma diagnostics. The ability ...
    • Effect of Disulfiram and Copper Plus Chemotherapy vs Chemotherapy Alone on Survival in Patients with Recurrent Glioblastoma: A Randomized Clinical Trial 

      Werlenius, Katja; Kinhult, Sara; Solheim, Tora S; Magelssen, Henriette; Löfgren, David; Mudaisi, Munila; Hylin, Sofia; Bartek, Jiri; Strandéus, Michael; Lindskog, Magnus; Rashid, Havyan Bahroz; Carstam, Louise; Gulati, Sasha; Solheim, Ole Skeidsvoll; Salvesen, Øyvind Olav; Jakola, Asgeir Store (Peer reviewed; Journal article, 2023)
      Importance Disulfiram has demonstrated broad antitumoral effect in several preclinical studies. One of the proposed indications is for the treatment of glioblastoma. Objective To evaluate the efficacy and safety of ...
    • Epidemiology and practice variations of shunt surgery for hydrocephalus: a nationwide registry-based study 

      Mansoor, Nadia; Gulati, Sasha; Fredriksli, Oddrun Anita; Salvesen, Øyvind Olav; Solheim, Ole Skeidsvoll (Peer reviewed; Journal article, 2023)
      OBJECTIVE Indications for surgical treatment of hydrocephalus (HC) can vary across centers. The authors sought to investigate the frequencies of surgically treated HC disorders and to study variations in the practice ...
    • Glioblastom hos voksne 

      Schipmann, Stephanie; Sivakanesan, Sarankan; Rath, Daniel Stavne; Brandal, Petter; Vik-Mo, Einar Osland; Bjørås, Magnar; Solheim, Ole Skeidsvoll; Ingebrigtsen, Tor; Sund, Fredrik; Bjerkvig, Rolf; Miletic, Hrvoje; Johannessen, Tor-Christian Aase; Sundstrøm, Terje (Peer reviewed; Journal article, 2023)
      lioblastom er den vanligste formen for primær hjernekreft hos voksne, og sykdommen har en alvorlig prognose. Selv om det er gjort store fremskritt i molekylær karakteristikk, har det ikke vært større gjennombrudd i ...
    • Long-term follow up of patients with WHO grade 2 oligodendroglioma 

      Carstam, Louise; Latini, Francesco; Solheim, Ole Skeidsvoll; Bartek, Jiri; Pedersen, Lars Kjelsberg; Zetterling, Maria; Beniaminov, Stanislav; Sjåvik, Kristin; Ryttlefors, Mats; Jensdottir, Margret; Rydenhag, Bertil; Smits, Anja; Jakola, Asgeir Store (Peer reviewed; Journal article, 2023)
      Purpose Since the introduction of the molecular definition of oligodendrogliomas based on isocitrate dehydrogenase (IDH)-status and the 1p19q-codeletion, it has become increasingly evident how this glioma entity differs ...
    • Meningiomas and Somatostatin Analogs: A Systematic Scoping Review on Current Insights and Future Perspectives 

      Tollefsen, Sofie Eline; Solheim, Ole Skeidsvoll; Mjønes, Patricia Gjertrud; Torp, Sverre Helge (Journal article; Peer reviewed, 2023)
    • On the prognostic factors of low-grade gliomas 

      Skjulsvik, Anne Jarstein (Doctoral theses at NTNU;2020:139, Doctoral thesis, 2020)
      Hjernesvulsters egenskaper i forløpet ved hjernekreft Gliomer er den vanligste typen av primære maligne hjernesvulster og disse rammer ca. 6 personer per 100 000 per år. Gliomer graderes ved mikroskopisk cellebilde og ...
    • Patient-reported cognitive function in patients with diffuse glioma 

      Schei, Stine (Doctoral theses at NTNU;2023:105, Doctoral thesis, 2023)
      Norsk sammendrag Kognitiv funksjon hos pasienter med diffust gliom – pasientenes perspektiv Diffuse gliomer er den vanligste typen primære ondartede hjernesvulster hos voksne. Basert på verdens helseorganisasjons ...
    • Predicting Regions of Local Recurrence in Glioblastomas Using Voxel-Based Radiomic Features of Multiparametric Postoperative MRI 

      Cepeda, Santiago; Luppino, Luigi Tommaso; Pérez-Núñez, Angel; Solheim, Ole Skeidsvoll; García-García, Sergio; Velasco-Casares, María; Karlberg, Anna Maria; Eikenes, Live; Sarabia, Rosario; Arrese, Ignacio; Zamora, Tomás; Gonzalez, Pedro; Jiménez-Roldán, Luis; Kuttner, Samuel (Peer reviewed; Journal article, 2023)
      The globally accepted surgical strategy in glioblastomas is removing the enhancing tumor. However, the peritumoral region harbors infiltration areas responsible for future tumor recurrence. This study aimed to evaluate a ...
    • Preoperative Prognostic Index for Patients with Brain Metastases—A Population-Based Multi-Centre Study 

      Winther, Rebecca Rootwelt; Skovlund, Eva; Andreassen, Joakim Stray; Arvidsson, Lisa; Halvardson, Jonathan; Solheim, Ole Skeidsvoll; Bartek, Jiri; Kaasa, Stein; Hjermstad, Marianne Jensen; Vik-Mo, Einar Osland (Peer reviewed; Journal article, 2023)
      Background: Brain metastases (BM) are common in cancer patients and are associated with high morbidity and mortality. Surgery is an option, but the optimal selection of patients for surgery is challenging and controversial. ...
    • Raidionics: an open software for pre- and postoperative central nervous system tumor segmentation and standardized reporting 

      Bouget, David Nicolas Jean-Mar; Alsinan, Demah; Gaitan, Valeria; Helland, Ragnhild Holden; Pedersen, Andre; Solheim, Ole Skeidsvoll; Reinertsen, Ingerid Reime (Peer reviewed; Journal article, 2023)
      For patients suffering from central nervous system tumors, prognosis estimation, treatment decisions, and postoperative assessments are made from the analysis of a set of magnetic resonance (MR) scans. Currently, the lack ...
    • Retrospective and registry-based studies on surgery for hydrocephalus in Norway 

      Mansoor, Nadia (Doctoral theses at NTNU;2023:283, Doctoral thesis, 2023)
      English summary Hydrocephalus is the term for the condition where the flow of the cerebrospinal fluid is halted or impeded. Hydrocephalus results in an increase in size of the ventricular system in the brain and raised ...
    • Segmentation of glioblastomas in early post-operative multi-modal MRI with deep neural networks 

      Helland, Ragnhild Holden; Ferles, Alexandros; Pedersen, Andre; Kommers, Ivar; Ardon, Hilko; Barkhof, Frederik; Bello, Lorenzo; Berger, Mitchel S.; Dunås, Tora; Nibali, Marco Conti; Furtner, Julia; Hervey-Jumper, Shawn; Idema, Albert J. S.; Kiesel, Barbara; Tewari, Rishi Nandoe; Mandonnet, Emmanuel; Müller, Domenique M. J.; Robe, Pierre A.; Rossi, Marco; Sagberg, Lisa Millgård; Sciortino, Tommaso; Aalders, Tom; Wagemakers, Michiel; Widhalm, Georg; Witte, Marnix G.; Zwinderman, Aeilko H.; Majewska, Paulina Luiza; Jakola, Asgeir Store; Solheim, Ole Skeidsvoll; Hamer, Philip C. De Witt; Reinertsen, Ingerid; Eijgelaar, Roelant S.; Bouget, David Nicolas Jean-Marie (Peer reviewed; Journal article, 2023)
      Extent of resection after surgery is one of the main prognostic factors for patients diagnosed with glioblastoma. To achieve this, accurate segmentation and classification of residual tumor from post-operative MR images ...
    • Volumetric segmentations for quantitative radiological evaluations in patients with high-grade glioma 

      Fyllingen, Even Hovig (Doctoral theses at NTNU;2020:130, Doctoral thesis, 2020)
      Sammendrag på norsk Volumsegmentering for kvantitative radiologiske vurderinger hos pasienter med høygradig gliom Diffuse høygradige gliomer er ondartede primære hjernesvulster. Glioblastom er den vanligste og mest ...